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Abstract

Feline lymphoplasmacytic pododermatitis is a rare dermatological condition, likely of immune-mediated origin, and still poorly described in the literature. This paper aims to report a clinical case, highlighting the diagnostic findings and therapeutic response. A four-year-old female mixed-breed cat was treated, presenting with a lesion on the left metacarpal pad, associated with local pain, lameness, and excessive licking. Initially, symptomatic treatment was instituted, considering the nonspecific nature of the lesions and the absence of systemic manifestations; however, there was no satisfactory clinical response. Therefore, complementary diagnostic investigation was carried out, with imaging and cytology exams, still inconclusive; the definitive diagnosis was established through histopathological examination, which showed lymphoplasmacytic infiltrate. Treatment based on immunosuppression with glucocorticoids, associated with the control of secondary infections, resulted in complete clinical remission. The importance of histopathological diagnosis is highlighted for confirming the disease and initiating appropriate therapy, as well as controlling possible opportunistic infections.